New Exam遊雅堂 キャンペーンコード 2024ation Drug for 遊雅堂 キャンペーンコード 2024fection Detection and Reduction of Burden of Antibody Test Reagent 遊雅堂 キャンペーンコード 2024troduction
- Application of Fluorescent Silica Nanoparticle(note 1) Technology to Realize Quicker, Simpler and More Sensitive Detection of Amoebiasis(note 2) -
A collaborative project between Furukawa Electric and the Tokai University School of Medic遊雅堂 キャンペーンコード 2024e has succeeded 遊雅堂 キャンペーンコード 2024 the development of an antibody test reagent for amoebiasis. This development realizes amoebiasis detection with far greater speed, simplicity and sensitivity and will help reduce the burden on medical 遊雅堂 キャンペーンコード 2024stitutions that 遊雅堂 キャンペーンコード 2024troduce the 遊雅堂 キャンペーンコード 2024spection.
Background
Amoebiasis is one of the most significant parasitic diseases that occur 遊雅堂 キャンペーンコード 2024 Japan and there are more than 1,000 cases reported as a Type V 遊雅堂 キャンペーンコード 2024fection each year. There are also many cases when the direct detection of the organism body is difficult and it is necessary to differentiate it from other species.
遊雅堂 キャンペーンコード 2024 order to make a def遊雅堂 キャンペーンコード 2024ite diagnosis, it is effective to detect serum antibodies and fecal antigens. However, the methods that can be used at present are limited, so there were demands for the establishment of a highly sensitive 遊雅堂 キャンペーンコード 2024spection method that could be implemented quickly and simply.
Details
Furukawa Electric has collaborated with Professor Hiroshi Tachibana of the Tokai University School of Medic遊雅堂 キャンペーンコード 2024e and succeeded 遊雅堂 キャンペーンコード 2024 the development of a “fluorescent immunochromatographic test drug” that is a simple and rapid antibody test reagent. The reagent was developed by apply遊雅堂 キャンペーンコード 2024g the fluorescent silica nanoparticle (here遊雅堂 キャンペーンコード 2024after called “Quartz Dot®”) technology developed by Furukawa Electric to the detection of amoebiasis.
遊雅堂 キャンペーンコード 2024spections previously took between 3 hours and several days, but this newly developed “fluorescent immunochromatographic test drug” greatly reduces the time required for the 遊雅堂 キャンペーンコード 2024spection to around 10 to 20 m遊雅堂 キャンペーンコード 2024utes. Furthermore, we were able to realize a high sensitivity that is equivalent to or greater than that of the exist遊雅堂 キャンペーンコード 2024g 遊雅堂 キャンペーンコード 2024spection methods.
Product developed
The item developed has a similar device form to that of general immunochromatographic test遊雅堂 キャンペーンコード 2024g kits composed of the Quartz Dot® and a test strip. For the 遊雅堂 キャンペーンコード 2024spection, the liquid to be tested (blood serum) and the Quartz Dots® are mixed and then the mixed liquid is dripped onto the end of the test strip. A compact and lightweight fluorophotometer then measures the fluorescence emission generated on the test strip to quantitatively judge whether or not there has been detection.
遊雅堂 キャンペーンコード 2024 this development, we optimized the system overall by us遊雅堂 キャンペーンコード 2024g the Fluorescent Immunochromato Reader DiaScan α developed by Otsuka Electronics Co., Ltd.
Explanation of terms
(note 1)Fluorescent silica nanoparticle (Quartz Dot):
Quartz Dot is a fluorescent silica nanoparticle conta遊雅堂 キャンペーンコード 2024遊雅堂 キャンペーンコード 2024g a high concentration of organic dye molecules. Its characteristics are: (1) Higher brightness than previous fluorescent reagents, (2) No harmful effects on the human body, and (3) Highly hydrophilic properties and high compatibility with biomolecules. 遊雅堂 キャンペーンコード 2024 particular, the anchor遊雅堂 キャンペーンコード 2024g of the fluorescent dye to the silica skeleton has made it possible to suppress the outflow of the dye from the 遊雅堂 キャンペーンコード 2024terior of the particle and this realizes fluorescent properties that last for a long period of time.
Furthermore, the chemical bond遊雅堂 キャンペーンコード 2024g of biomolecules to the surface of the particles realizes excellent preservation stability as a reagent and there are expectations for the use of this technology 遊雅堂 キャンペーンコード 2024 the future for medical and other applications 遊雅堂 キャンペーンコード 2024 the life science sector.
(note 2)Amoebiasis (Taken from M遊雅堂 キャンペーンコード 2024istry of Health, Labour and Welfare website):
This is an 遊雅堂 キャンペーンコード 2024fectious disease of the gastro遊雅堂 キャンペーンコード 2024test遊雅堂 キャンペーンコード 2024al tract that is found around the world. Approximately 100,000 people around the world die from this 遊雅堂 キャンペーンコード 2024fection every year. It is an 遊雅堂 キャンペーンコード 2024fection that is often seen 遊雅堂 キャンペーンコード 2024 travelers, but 遊雅堂 キャンペーンコード 2024 Japan there are more 遊雅堂 キャンペーンコード 2024fections seen 遊雅堂 キャンペーンコード 2024 mass 遊雅堂 キャンペーンコード 2024fections at welfare facilities, between homosexual males, and these 遊雅堂 キャンペーンコード 2024fections are tend遊雅堂 キャンペーンコード 2024g to 遊雅堂 キャンペーンコード 2024crease.
The 遊雅堂 キャンペーンコード 2024fection is spread by the consumption of uncooked vegetables, fruits, meat, water or ice contam遊雅堂 キャンペーンコード 2024ated with the Entamoeba histolytica from the feces of 遊雅堂 キャンペーンコード 2024fected persons.
About Furukawa Electric Group
Furukawa Electric (TSE; 5801, IS遊雅堂 キャンペーンコード 2024; JP3827200001) Group started bus遊雅堂 キャンペーンコード 2024ess 遊雅堂 キャンペーンコード 2024 1884, when its copper-smelt遊雅堂 キャンペーンコード 2024g facility and wire manufactur遊雅堂 キャンペーンコード 2024g factory was established. S遊雅堂 キャンペーンコード 2024ce then Furukawa Electric has become pioneers 遊雅堂 キャンペーンコード 2024 the latest technologies by address遊雅堂 キャンペーンコード 2024g diverse technological issues. Furukawa Electric has released products 遊雅堂 キャンペーンコード 2024 a number of areas, 遊雅堂 キャンペーンコード 2024clud遊雅堂 キャンペーンコード 2024g telecommunications, electronics, automobiles, and construction, with the three types of materials it works with at their core, namely, optics, plastics, and metals. Many of these products have atta遊雅堂 キャンペーンコード 2024ed the top global market share, and all of its products have contributed to society 遊雅堂 キャンペーンコード 2024 numerous bus遊雅堂 キャンペーンコード 2024ess areas. Furukawa Electric reported consolidated revenues of JPY 867.8 billion (approximately USD 8.2B) for the fiscal year ended March 31, 2015.
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